Card Trivia:Ultra Evolution Pill
- This card has an upgraded form: "Big Evolution Pill".
- This card has two counterparts: "Double Evolution Pill" and "New Ultra Evolution".
- This card's effect of Tributing a Reptile monster to Special Summon a Dinosaur monster from the player's hand is based on the theory that dinosaurs evolved from reptiles, arising from the archosaurimorphs. The card's artwork depicts a crocodilian creature, with crocodiles believed to be the closest living reptile to ancestral dinosaurs.
- In the English dubbed version of the Yu-Gi-Oh! anime, this card is referred to as "Ultra Evolution". At the time that this card appeared in the anime, FCC regulations prohibited the depiction of drugs; also, the pill that appears in this card's artwork was also digitally removed.